STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiAGlucose-6-phosphate isomerase, archaeal (pgiA); Belongs to the archaeal-type GPI family. (189 aa)    
Predicted Functional Partners:
hps
3-hexulose-6-phosphate synthase-6-phospho 3-hexuloisomerase fused bifuntional enzyme (hps).
 
 
 0.980
glkA
ADP-dependent glucokinase (glkA); Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor.
 
  
 0.941
pfkC
ADP-specific phosphofructokinase (pfkC); Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
    
 0.919
scrK
Fructokinase (scrK); 1 probable transmembrane helix predicted by modhmm.
 
 
 0.918
tk-2
Transketolase N-terminal section (tk).
  
  
  0.913
pgm
Phosphoglucomutase (pgm).
    
  0.911
manA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase, bifunctional enzyme (manA/manC); Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.911
tk-1
Transketolase C-terminal section (tk).
  
  
  0.911
fbp
Fructose-1,6-bisphosphatase (FBPase V) (fbp); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.906
glmS-1
Glucosamine--fructose-6-phosphate aminotransferase, sugar isomerase (SIS) domain (glmS); 1 probable transmembrane helix predicted by modhmm.
    
  0.900
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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