Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mntBManganese ABC-type transporter ATP-binding protein (mntB). (264 aa)    
Predicted Functional Partners:
mntC
Manganese ABC-type transporter, permease component (mntC); 9 probable transmembrane helices predicted by modhmm.
 
 
 0.998
TGAM_1644
ABC-type transporter, periplasmic component, surface adhesin; 2 probable transmembrane helices predicted by modhmm.
 
  
 0.956
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.914
eIF1A
eIF1A translation initiation factor eIF-1A (eIF1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
       0.624
rio1
Protein serine/threonine kinase, RIO1 family (rio1).
       0.585
TGAM_1424
RNA-binding protein, containing KH domain.
       0.583
top6B
Type II DNA topoisomerase VI, subunit B (Top6B); Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.583
top6A
Type II DNA topoisomerase VI, subunit A (Top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.583
TGAM_1427
Conserved hypothetical protein; Belongs to DUF530 family.
       0.583
TGAM_1428
Conserved hypothetical protein; Contains 1 Homeodomain-like domain in C-term.
       0.583
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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