Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_1102Predicted ATPase of the PP-loop superfamily. (262 aa)    
Predicted Functional Partners:
hypE-1
Hydrogenase expression/formation related protein (hypE).
   
   0.917
TGAM_1099
HEPN-type nucleotidyltransferase, antibiotic resistance related; Contains one HEPN domain in C-term.
       0.871
feoA
Fe2+ transport protein A, putative (FeoA).
     
 0.809
feoB
Fe2+ transport protein B (feoB); 6 probable transmembrane helices predicted by modhmm.
       0.806
TGAM_1106
Conserved hypothetical protein; Putative DNA-binding proetin, contains one 'Winged helix' DNA-binding domain.
       0.806
TGAM_1100
Nucleotidyltransferase.
       0.740
TGAM_1103
Hypothetical protein; 6 probable transmembrane helices predicted by modhmm.
       0.714
TGAM_1107
Sugar-phosphate nucleotydyltransferase.
  
 
 0.689
TGAM_0154
Conserved hypothetical protein; Belongs to Radical SAM family.
 
     0.562
TGAM_0547
Conserved hypothetical protein; Belongs to DUF364 family, contains NAD(P)-binding Rossmann-fold domain (SSF51735).
  
    0.560
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (16%) [HD]