Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_1114Membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase; 10 probable transmembrane helices predicted by modhmm. (733 aa)    
Predicted Functional Partners:
TGAM_1113
Conserved hypothetical protein; 12 probable transmembrane helices predicted by modhmm.
       0.841
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
  
     0.643
dpm1-2
Dolichol-phosphate mannosyltransferase (dpm1); 2 probable transmembrane helices predicted by modhmm.
 
   
 0.619
TGAM_1675
Arginase related protein; Belongs to the arginase family.
  
     0.539
TGAM_0661
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
  
     0.517
TGAM_1748
Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; Contains 3 TRP repeats.
 
     0.507
TGAM_1709
Conserved hypothetical protein; Ref AJ132781.1 (Thermococcus hydrothermalis alpha-glucosidase)is not correct !!; 3 probable transmembrane helices predicted by modhmm.
  
     0.493
TGAM_1314
Voltage-gated potassium channel, putative; 2 probable transmembrane helices predicted by modhmm.
  
     0.484
TGAM_1522
Conserved hypothetical protein.
  
     0.481
TGAM_2006
Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; Contains 3 TRP repeats.
 
     0.476
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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