Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
TGAM_1192Base excision DNA repair protein, HhH-GPD superfamily. (278 aa)    
Predicted Functional Partners:
TGAM_1190
Conserved hypothetical protein.
       0.914
TGAM_1191
Conserved hypothetical protein.
       0.914
TGAM_0365
Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.
   
 0.902
TGAM_1193
ATPase, putative, PP-loop superfamily.
       0.899
TGAM_1903
Conserved hypothetical protein.
     
 0.778
nfeD
Membrane bound protease, putative, nfeD/ClpP- family (nfeD); 4 probable transmembrane helices predicted by modhmm.
 
     0.689
nth
Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.668
hef
Hef, Helicase-associated endonuclease for fork-structured DNA (Hef).
  
 
   0.667
TGAM_1446
Endonuclease IV, AP endonuclease family 2.
   
 
 0.666
TGAM_1901
Membrane permease, stomatin-like protein; 1 probable transmembrane helix predicted by modhmm.
  
    0.655
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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