TGAM_1200 protein (Thermococcus gammatolerans)

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TGAM_1200

Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm. (155 aa)

Predicted Functional Partners:

fen

0.827

acdA-5

0.809

TGAM_1203

0.509

TGAM_1202

0.412

Your Current Organism:

Thermococcus gammatolerans

NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TGAM_1200	TGAM_1202	TGAM_1200	TGAM_1202	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	0.412
TGAM_1200	TGAM_1203	TGAM_1200	TGAM_1203	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	0.509
TGAM_1200	acdA-5	TGAM_1200	TGAM_1201	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	0.809
TGAM_1200	fen	TGAM_1200	TGAM_1199	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	0.827
TGAM_1202	TGAM_1200	TGAM_1202	TGAM_1200	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	0.412
TGAM_1202	TGAM_1203	TGAM_1202	TGAM_1203	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	0.863
TGAM_1202	acdA-5	TGAM_1202	TGAM_1201	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	0.730
TGAM_1203	TGAM_1200	TGAM_1203	TGAM_1200	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	0.509
TGAM_1203	TGAM_1202	TGAM_1203	TGAM_1202	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	0.863
TGAM_1203	acdA-5	TGAM_1203	TGAM_1201	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	0.829
TGAM_1203	fen	TGAM_1203	TGAM_1199	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	0.519
acdA-5	TGAM_1200	TGAM_1201	TGAM_1200	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	0.809
acdA-5	TGAM_1202	TGAM_1201	TGAM_1202	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.	0.730
acdA-5	TGAM_1203	TGAM_1201	TGAM_1203	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	0.829
acdA-5	fen	TGAM_1201	TGAM_1199	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	0.741
fen	TGAM_1200	TGAM_1199	TGAM_1200	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	Conserved hypothetical membrane protein; 2 probable transmembrane helices predicted by modhmm.	0.827
fen	TGAM_1203	TGAM_1199	TGAM_1203	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	Metallophosphoesterase, MJ0912 type; Contains 1 calcineurin-like phosphoesterase domain.	0.519
fen	acdA-5	TGAM_1199	TGAM_1201	Flap structure-specific endonuclease (fen); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]	Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).	0.741

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