Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiA4-hydroxybenzoate polyprenyltransferase, putative (UbiA); 8 probable transmembrane helices predicted by modhmm. (298 aa)    
Predicted Functional Partners:
ubiD-1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase (UbiD).
 
  
 0.993
ubiX
3-octaprenyl-4-hydroxybenzoate decarboxylase (UbiX); Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.952
TGAM_1229
ABC transporter, periplasmic protein, putative taurine-binding protein; 1 probable transmembrane helix predicted by modhmm.
     
 0.801
TGAM_1228
ABC transporter, permease protein; 7 probable transmembrane helices predicted by modhmm.
       0.800
cydA
Cytochrome bd ubiquinol oxidase, subunit I (cydA); 9 probable transmembrane helices predicted by modhmm.
     
 0.520
cydB
Cytochrome bd ubiquinol oxidase, subunit II (cydB); 9 probable transmembrane helices predicted by modhmm.
       0.515
aroC
Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
   
 
 0.498
TGAM_1240
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.496
aroD
3-dehydroquinate dehydratase (aroD); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
     
 0.478
hemH
Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
   
 0.463
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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