Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_1344Conserved hypothetical protein; Belongs to DUF555 family; Belongs to the UPF0212 family. (128 aa)    
Predicted Functional Partners:
TGAM_1345
Conserved hypothetical protein; Belongs to DUF357 family.
 
     0.924
TGAM_1343
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.794
TGAM_1342
Metal-dependent hydrolase/oxidoreductase, beta-lactamase family.
       0.706
TGAM_1460
recJ-like phosphoesterase, containing RNA binding S1 and OB-fold nucleic acid binding domain.
  
     0.652
TGAM_1553
Transcription regulator, ArsR family; 2 probable transmembrane helices predicted by modhmm.
  
     0.633
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.612
TGAM_1346
Hydrolase, HAD superfamily.
       0.609
TGAM_1347
Conserved hypothetical protein; Belongs to DUF437.
       0.609
TGAM_1193
ATPase, putative, PP-loop superfamily.
  
    0.602
TGAM_0029
Conserved hypothetical protein; Belongs to DUF460 family.
  
     0.592
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.