STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trm1N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (378 aa)    
Predicted Functional Partners:
rpl35AE
LSU ribosomal protein L35AE (rpl35AE); Belongs to the eukaryotic ribosomal protein eL33 family.
       0.717
truD
tRNA pseudouridylate synthase D (TruD); Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
 
 0.663
TGAM_0464
pre-mRNA splicing, snoRNA binding protein, NOP5/NOP56 related.
 
    0.662
TGAM_1424
RNA-binding protein, containing KH domain.
  
   0.637
tmcA
Predicted P-loop ATPase fused to an acetyltransferase (GNAT) family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
  
 0.634
truB
Centromere binding protein CBF5/pseudouridine synthase truB-like protein (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.610
truA
tRNA-pseudouridine synthase A (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
 
 0.599
TGAM_0645
GTPase, NOG1/MMR-HSR1 family; Belongs to G-protein superfamily.
 
   0.582
rpoH
DNA-directed RNA polymerase subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
   0.577
TGAM_1186
Nucleotide binding protein, putative, containing PIN domain.
  
    0.571
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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