Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
egsAGlycerol-1-phosphate dehydrogenase [NAD(P)] (egsA); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (349 aa)    
Predicted Functional Partners:
gggPS
Geranylgeranylglyceryl phosphate synthase (GGGPS); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.954
TGAM_1401
Conserved hypothetical protein; Belongs to UPF0179 family.
 
   
 0.917
glpA-1
Anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative (glpA).
    
  0.901
glpA-2
Anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative (glpA).
    
  0.901
TGAM_1403
Predicted membrane protein; Belongs to DUF63 family; 5 probable transmembrane helices predicted by modhmm.
     
 0.839
TGAM_1405
Peptidase, putative, Rhomboid-like protein protein; 6 probable transmembrane helices predicted by modhmm.
  
    0.838
suhB
Inositol-1-monophosphatase (suhB); 1 probable transmembrane helix predicted by modhmm.
       0.826
purD
Phosphoribosylamine--glycine ligase (purD).
 
   
 0.674
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.626
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
   
 0.620
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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