Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
TGAM_1492Conserved hypothetical protein. (108 aa)    
Predicted Functional Partners:
TGAM_1493
Phosphoesterase, recJ-like, containing a DHHA1 domain.
       0.914
TGAM_1494
Conserved hypothetical protein.
       0.914
gimC
Prefoldin, beta subunit (gimC); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
       0.905
TGAM_1497
Conserved hypothetical protein.
       0.759
TGAM_1498
Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
       0.738
TGAM_1416
tRNA-binding protein, putative.
       0.649
TGAM_1418
Conserved hypothetical protein.
       0.649
TGAM_1496
Hypothetical protein; 4 probable transmembrane helices predicted by modhmm.
       0.542
rpoP
DNA-directed RNA polymerase subunit P (rpoP); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
       0.408
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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