TGAM_1503 protein (Thermococcus gammatolerans)

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Score

TGAM_1503

Conserved hypothetical protein. (151 aa)

Predicted Functional Partners:

TGAM_1502

0.914

TGAM_1501

0.910

TGAM_1499

0.755

panB

0.755

TGAM_1504

0.508

rtcB

0.500

Your Current Organism:

Thermococcus gammatolerans

NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TGAM_1499	TGAM_1501	TGAM_1499	TGAM_1501	Dolichol-phosphate mannosyltransferase.	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	0.763
TGAM_1499	TGAM_1502	TGAM_1499	TGAM_1502	Dolichol-phosphate mannosyltransferase.	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.755
TGAM_1499	TGAM_1503	TGAM_1499	TGAM_1503	Dolichol-phosphate mannosyltransferase.	Conserved hypothetical protein.	0.755
TGAM_1499	panB	TGAM_1499	TGAM_1500	Dolichol-phosphate mannosyltransferase.	3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.	0.914
TGAM_1501	TGAM_1499	TGAM_1501	TGAM_1499	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	Dolichol-phosphate mannosyltransferase.	0.763
TGAM_1501	TGAM_1502	TGAM_1501	TGAM_1502	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.943
TGAM_1501	TGAM_1503	TGAM_1501	TGAM_1503	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	Conserved hypothetical protein.	0.910
TGAM_1501	TGAM_1504	TGAM_1501	TGAM_1504	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	Contains quinoprotein alcohol dehydrogenase-like signature; 2 probable transmembrane helices predicted by modhmm.	0.501
TGAM_1501	panB	TGAM_1501	TGAM_1500	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.	0.756
TGAM_1501	rtcB	TGAM_1501	TGAM_1505	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	Conserved hypothetical protein; Belongs to UPF0027 family; Belongs to the RtcB family.	0.985
TGAM_1502	TGAM_1499	TGAM_1502	TGAM_1499	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Dolichol-phosphate mannosyltransferase.	0.755
TGAM_1502	TGAM_1501	TGAM_1502	TGAM_1501	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	0.943
TGAM_1502	TGAM_1503	TGAM_1502	TGAM_1503	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Conserved hypothetical protein.	0.914
TGAM_1502	TGAM_1504	TGAM_1502	TGAM_1504	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Contains quinoprotein alcohol dehydrogenase-like signature; 2 probable transmembrane helices predicted by modhmm.	0.508
TGAM_1502	panB	TGAM_1502	TGAM_1500	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.	0.775
TGAM_1502	rtcB	TGAM_1502	TGAM_1505	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Conserved hypothetical protein; Belongs to UPF0027 family; Belongs to the RtcB family.	0.500
TGAM_1503	TGAM_1499	TGAM_1503	TGAM_1499	Conserved hypothetical protein.	Dolichol-phosphate mannosyltransferase.	0.755
TGAM_1503	TGAM_1501	TGAM_1503	TGAM_1501	Conserved hypothetical protein.	Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).	0.910
TGAM_1503	TGAM_1502	TGAM_1503	TGAM_1502	Conserved hypothetical protein.	SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.914
TGAM_1503	TGAM_1504	TGAM_1503	TGAM_1504	Conserved hypothetical protein.	Contains quinoprotein alcohol dehydrogenase-like signature; 2 probable transmembrane helices predicted by modhmm.	0.508

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