Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_1546CAAX amino terminal family protease; 4 probable transmembrane helices predicted by modhmm. (202 aa)    
Predicted Functional Partners:
TGAM_1547
Conserved hypothetical protein.
       0.914
slyD-2
FKBP-type peptidyl-prolyl cis-trans isomerase (slyD).
       0.833
cysS
Cysteinyl-tRNA synthetase (cysS).
  
    0.785
TGAM_1274
Nitroreductase.
  
  
 0.522
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
 
     0.446
TGAM_2076
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
  
     0.439
TGAM_0836
ABC-type multidrug transporter permease protein; 6 probable transmembrane helices predicted by modhmm.
  
  
 0.409
TGAM_1370
ABC-2 type transport system permease component, putative; 6 probable transmembrane helices predicted by modhmm.
  
  
 0.409
TGAM_1488
ABC-type transport system, permease component; Belongs to family 2 of ABC transporters; 6 probable transmembrane helices predicted by modhmm.
  
  
 0.409
TGAM_1698
ABC-type transporter, ATP-binding component; 6 probable transmembrane helices predicted by modhmm.
  
  
 0.409
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.