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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tk-2Transketolase N-terminal section (tk). (219 aa)    
Predicted Functional Partners:
tk-1
Transketolase C-terminal section (tk).
 0.999
rpiA
Ribose-5-phosphate isomerase (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.915
pgiA
Glucose-6-phosphate isomerase, archaeal (pgiA); Belongs to the archaeal-type GPI family.
  
  
  0.913
prs
Ribose-phosphate pyrophosphokinase (prs); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
    
 0.913
pfkC
ADP-specific phosphofructokinase (pfkC); Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
  
  
  0.911
hps
3-hexulose-6-phosphate synthase-6-phospho 3-hexuloisomerase fused bifuntional enzyme (hps).
    
  0.910
deoC
Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.905
deoB
Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family.
    
 0.905
pgm
Phosphoglucomutase (pgm).
    
 0.905
fba
Fructose 1,6-bisphosphate aldolase class 1 (fba).
    
  0.905
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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