Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
crcBChromosome condensation protein, crcB-like protein (crcB); Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (123 aa)    
Predicted Functional Partners:
TGAM_1672
Conserved hypothetical protein; Belongs to GlnB-like superfamily.
 
   
 0.935
exsB
Transcription regulator, putative, ExsB family (ExsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
     
 0.919
TGAM_1674
Conserved hypothetical protein.
     
 0.800
TGAM_1671
Conserved hypothetical protein.
       0.784
coaBC
Coenzyme A biosynthesis bifunctional protein coaBC (coaBC); Includes Phosphopantothenoylcysteine decarboxylase and Phosphopantothenate--cysteine ligase.
 
     0.771
TGAM_1166
Zinc metallopeptidase.
       0.641
rnj
RNA-metabolising metallo-beta-lactamase, beta-CASP family protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
     
 0.487
TGAM_0973
Voltage-gated potassium channel, putative; 2 probable transmembrane helices predicted by modhmm.
  
    0.456
mntC
Manganese ABC-type transporter, permease component (mntC); 9 probable transmembrane helices predicted by modhmm.
 
   
 0.421
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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