Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
eif6Translation initiation factor 6 (eif6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (228 aa)    
Predicted Functional Partners:
rplXA
LSU ribosomal protein LXA (rplXA).
 
 
 0.996
rpl31E
LSU ribosomal protein L31E (rpl31E); Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.996
rpl3P
LSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.976
rpl7AE
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.969
rpl30E
LSU ribosomal protein L30E (rpl30E); Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
 0.960
rpl34E
LSU ribosomal protein L34E (rpl34E); Belongs to the eukaryotic ribosomal protein eL34 family.
  
 
 0.945
rpl11P
LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.944
rpl14P
LSU ribosomal protein L14P (rpl14P); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
 
 0.944
rpl24E
LSU ribosomal protein L24E (rpl24E); Binds to the 23S rRNA.
 
 
 0.943
rpl24P
LSU ribosomal protein L24P (rpl24P); Located at the polypeptide exit tunnel on the outside of the subunit.
 
 
 0.941
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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