Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_1702Phospholipase C/P1 nuclease family protein, putative; 1 probable transmembrane helix predicted by modhmm. (444 aa)    
Predicted Functional Partners:
TGAM_1703
Hydrolase, HAD superfamily, putative.
       0.832
gcvP1
Glycine dehydrogenase [decarboxylating] subunit 1 (glycine cleavage system P- protein) (gcvP1); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
       0.826
gcvP2
Glycine dehydrogenase [decarboxylating] subunit 2 (glycine cleavage system P- protein) (gcvP2); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
       0.825
TGAM_1704
ABC-type transport system, permease component; 12 probable transmembrane helices predicted by modhmm.
       0.562
TGAM_1705
ABC-type transport system, ATPase component, putative Fe3+ transporter; Contains 2 facilitated glucose transporter signatures.
       0.555
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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