Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_1709Conserved hypothetical protein; Ref AJ132781.1 (Thermococcus hydrothermalis alpha-glucosidase)is not correct !!; 3 probable transmembrane helices predicted by modhmm. (242 aa)    
Predicted Functional Partners:
TGAM_1707
Sodium-dependent transporter, SNF family; 12 probable transmembrane helices predicted by modhmm; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
 
     0.936
TGAM_1708
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.718
TGAM_1675
Arginase related protein; Belongs to the arginase family.
  
     0.562
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
  
     0.539
TGAM_1114
Membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase; 10 probable transmembrane helices predicted by modhmm.
  
     0.493
TGAM_1314
Voltage-gated potassium channel, putative; 2 probable transmembrane helices predicted by modhmm.
  
     0.452
sfuA
ABC-type thiamine transport system, periplasmic component (sfuA); 1 probable transmembrane helix predicted by modhmm.
       0.403
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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