Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
glySGlycyl-tRNA synthetase (glyS); Catalyzes the attachment of glycine to tRNA(Gly). (570 aa)    
Predicted Functional Partners:
TGAM_1738
Small nuclear ribonucleoprotein (snRNP)-like protein, Sm-like protein; Belongs to the snRNP Sm proteins family.
       0.825
rpl37E
LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
    0.809
leuS
Leucyl-tRNA synthetase (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.784
ileS
Isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.767
proS
Prolyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
 
 
 0.731
TGAM_1663
Conserved hypothetical protein; Belongs to DUF402 family.
 
     0.695
argS
Arginyl-tRNA synthetase (argS); Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.690
aspS
Aspartyl-tRNA synthetase (aspS); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
 
 
 0.636
valS
Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.627
TGAM_1666
Conserved hypothetical protein; Belongs to the UPF0235 family.
       0.627
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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