STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribLCytidylyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (151 aa)    
Predicted Functional Partners:
ribK
Transcription regulator, putative; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
  
 0.933
TGAM_1845
RNA binding protein, containing PUA domain.
       0.800
pyrF
Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.800
TGAM_1847
Conserved hypothetical protein.
       0.800
ino1
Myo-inositol-1-phosphate synthase (ino1).
     
 0.751
TGAM_1853
Bifunctional phosphosugar nucleotidyltransferase/CDP-alcohol phosphatidyltransferase; 2 probable transmembrane helices predicted by modhmm; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.568
dpm1-2
Dolichol-phosphate mannosyltransferase (dpm1); 2 probable transmembrane helices predicted by modhmm.
  
  
 0.553
ribH
Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase) (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.520
sgaA
Aminotransferase, class V, putative serine-glyoxylate aminotransferase (sgaA).
  
  
 0.507
pyrD
Dihydroorotase dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate.
     
 0.407
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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