Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nfeDMembrane bound protease, putative, nfeD/ClpP- family (nfeD); 4 probable transmembrane helices predicted by modhmm. (454 aa)    
Predicted Functional Partners:
TGAM_1901
Membrane permease, stomatin-like protein; 1 probable transmembrane helix predicted by modhmm.
 
  
 0.971
TGAM_1903
Conserved hypothetical protein.
       0.834
TGAM_1192
Base excision DNA repair protein, HhH-GPD superfamily.
 
     0.689
TGAM_1190
Conserved hypothetical protein.
       0.649
TGAM_1191
Conserved hypothetical protein.
       0.649
minD-1
Cell division ATPase MinD (minD).
       0.649
TGAM_1784
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.649
pyrE
Orotate phosphoribosyltransferase (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.640
nefD-1
Nodulation efficiency protein D related protein (nefD); Belongs to DUF107 family; 3 probable transmembrane helices predicted by modhmm.
  
  
 0.522
nefD-2
Nodulation efficiency protein D related protein (nefD); 2 probable transmembrane helices predicted by modhmm.
  
  
 0.522
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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