Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TGAM_1909Conserved hypothetical protein; Belongs to DUF89 family. (286 aa)    
Predicted Functional Partners:
TGAM_1951
Conserved hypothetical protein.
       0.649
thiL
Thiamine monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
      0.496
TGAM_0842
Dinitrogenase iron-molybdenum cofactor, NIF B/Y/X related.
 
     0.423
TGAM_0569
ATPase, ParA type/MinD superfamily, containing an inserted ferredoxin domain.
 
     0.416
TGAM_0557
Dinitrogenase iron-molybdenum cofactor, NIF B/Y/X related.
 
     0.403
TGAM_0570
ATPase, ParA type/MinD superfamily, containing an inserted ferredoxin domain.
 
     0.400
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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