STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truBCentromere binding protein CBF5/pseudouridine synthase truB-like protein (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa)    
Predicted Functional Partners:
gar1
Gar1-like small nucleolar rnp, putative (gar1).
   
 0.999
nop10
Nucleolar RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.999
rpl7AE
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.991
TGAM_0464
pre-mRNA splicing, snoRNA binding protein, NOP5/NOP56 related.
 
 
 0.985
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
 
 0.977
cmk
Cytidylate kinase, putative (cmk); 1 probable transmembrane helix predicted by modhmm.
      0.938
rpoD
DNA-directed RNA polymerase subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
 
 
 0.880
guaA_C
GMP synthase [glutamine-hydrolyzing] pyrophosphatase subunit (C terminal domain) (guaA_C); Catalyzes the synthesis of GMP from XMP.
  
  
 0.870
rps15P
SSU ribosomal protein S15P (rps15P).
 
 
 0.862
tmcA
Predicted P-loop ATPase fused to an acetyltransferase (GNAT) family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 
 0.817
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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