Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_1977Conserved hypothetical protein; Belongs to DUF106 family; 3 probable transmembrane helices predicted by modhmm. (173 aa)    
Predicted Functional Partners:
adkA
Archaeal adenylate kinase (ATP-AMP transphosphorylase) (adkA); Belongs to the archaeal adenylate kinase family.
 
    0.958
cmk
Cytidylate kinase, putative (cmk); 1 probable transmembrane helix predicted by modhmm.
 
     0.885
rpl34E
LSU ribosomal protein L34E (rpl34E); Belongs to the eukaryotic ribosomal protein eL34 family.
 
     0.884
secY
Preprotein translocase secY subunit (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.878
rpl14E
LSU ribosomal protein L14E (rpl14E); Belongs to the eukaryotic ribosomal protein eL14 family.
       0.867
rpl15P
LSU ribosomal protein L15P (rpl15P); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
    0.867
rps5P
SSU ribosomal protein S5P (rps5P); With S4 and S12 plays an important role in translational accuracy.
  
    0.844
rpl30P
LSU ribosomal protein L30P (rpl30P).
 
    0.841
rpl32E
LSU ribosomal protein L32E (rpl32E); Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.831
rpl29P
LSU ribosomal protein L29P (rpl29P); Belongs to the universal ribosomal protein uL29 family.
 
    0.829
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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