STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
TGAM_2005ATP-dependent DNA ligase, putative; Contains 1 Ligase domain (PF01068) and has good convergence with psi-blast. Belongs to Y414 family. (380 aa)    
Predicted Functional Partners:
TGAM_0479
Nucleotide-binding protein, putative; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.819
lig
ATP-dependent DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family.
      
 0.783
rpl10E-2
LSU ribosomal protein L10 (rpl10E); Belongs to the universal ribosomal protein uL16 family.
       0.771
TGAM_2006
Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; Contains 3 TRP repeats.
       0.680
TGAM_2011
Permease, major facilitator superfamily; 11 probable transmembrane helices predicted by modhmm.
       0.594
TGAM_2008
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.556
TGAM_2009
Cysteine proteinase, putative; Contains SSF54001 signature and good convergence with psi-last; 1 probable transmembrane helix predicted by modhmm.
       0.556
TGAM_2007
Conserved hypothetical protein; Good similarity with a small orf in PH0954 downstream region.
       0.554
pol
DNA-directed DNA polymerase, B family (pol).
 
    0.510
atpC
Archaeal/vacuolar-type H+ ATPase, subunit C (atpC); Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
   
 0.500
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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