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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgaAAminotransferase, class V, putative serine-glyoxylate aminotransferase (sgaA). (384 aa)    
Predicted Functional Partners:
TGAM_2013
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.752
purD
Phosphoribosylamine--glycine ligase (purD).
 
  
 0.644
eno-1
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.626
TGAM_1072
Putative phosphoglycolate phosphatase fused to dolichol-phosphate mannose synthase (pgp/Dpm1).
     
 0.626
TGAM_2011
Permease, major facilitator superfamily; 11 probable transmembrane helices predicted by modhmm.
  
  
 0.618
rpl40E
LSU ribosomal protein L40E (rpl40E); Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
  0.605
serA
D-3-phosphoglycerate dehydrogenase, putative (serA); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.600
alaS
Alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.585
gcvT
Glycine cleavage system T protein (aminomethyltransferase) (gcvT); The glycine cleavage system catalyzes the degradation of glycine.
 
  
 0.559
fni
Isopentenyl-diphosphate delta-isomerase (fni); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.558
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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