Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
uspA-2Universal stress DNA-binding protein (UspA). (151 aa)    
Predicted Functional Partners:
arsB
Arsenical pump membrane protein (arsB); 12 probable transmembrane helices predicted by modhmm.
     
 0.921
TGAM_2110
Conserved hypothetical protein.
       0.905
engB
GTP-binding protein, HSR1-related; Necessary for normal cell division and for the maintenance of normal septation.
   
 
 0.854
lon
Archaeal serine protease, Lon protease-like protein (lon); 3 probable transmembrane helices predicted by modhmm; Belongs to the peptidase S16 family.
       0.827
TGAM_0730
Conserved hypothetical protein, Inosine-5'P dehydrogenase related protein; Contains 2 CBS domains pairs.
  
    0.654
TGAM_2030
Conserved hypothetical protein; Contains 4 CBS domains.
 
    0.563
gap
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap).
 
  
 0.538
speB
Agmatinase, putative, arginase family protein (speB); Belongs to the arginase family.
       0.534
ogt
Methylated-DNA--protein-cysteine methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.482
maeB
Malic enzyme (malate oxidoreductase) (maeB).
  
  
 0.455
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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