Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_2114Conserved hypothetical protein; Belongs to DUF431 family. (212 aa)    
Predicted Functional Partners:
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase (UbiE).
  
  
 0.842
TGAM_2112
Phosphoadenosine phosphosulfate (PAPS) reductase related protein.
 
     0.625
TGAM_2115
Hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.608
TGAM_0302
Conserved hypothetical protein; Contains CBS domain pair (PF00571).
 
    0.452
TGAM_1498
Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
    0.445
TGAM_1186
Nucleotide binding protein, putative, containing PIN domain.
  
    0.423
TGAM_1849
Extracellular solute binding protein, substrate unknown; 1 probable transmembrane helix predicted by modhmm.
  
     0.408
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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