Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGAM_2117Nucleotide-binding protein, containing HEPN domain; Disrupted by a frameshift. (61 aa)    
Predicted Functional Partners:
TGAM_2118
Conserved hypothetical protein.
       0.777
TGAM_2119
Conserved hypothetical protein; Belongs to UPF0175 family, contains 1 helix-turn-helix, Fis-type domain.
       0.554
TGAM_2120
Predicted nucleic acid-binding protein contains PIN domain, N-term part; Possible inframe shift with tg2121.
       0.551
TGAM_2116
Nucleotidyltransferase containing PAP/25A core domain, putative.
   
   0.512
TGAM_2121
Predicted nucleic acid-binding protein contains PIN domain, C-term part; Possible inframe shift with tg2120.
       0.493
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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