Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
TGAM_2123Conserved hypothetical protein; Contains probably 1 tRNA-binding domain (SSF46589) in Nterm and 1 t-snare domain (SSF47661) in Cterm. (301 aa)    
Predicted Functional Partners:
TGAM_2122
RNA-binding protein, containing PUA domain.
 
  
 0.985
cpkA
Carbamate kinase (Carbamate kinase-like carbamoylphosphate synthetase) (cpkA).
       0.649
TGAM_2118
Conserved hypothetical protein.
       0.649
TGAM_1303
Transcription regulator, arsR family, putative.
  
     0.622
TGAM_0854
Bacterial regulatory protein, arsR family.
  
     0.580
TGAM_0448
Conserved hypothetical protein; Contains DUF114 domain, putative ClpP protease; 1 probable transmembrane helix predicted by modhmm.
       0.577
TGAM_2124
Metallophosphoesterase, calcineurin superfamily; 1 probable transmembrane helix predicted by modhmm.
       0.576
TGAM_1522
Conserved hypothetical protein.
  
     0.571
pfdA-1
Prefoldin alpha subunit (pfdA); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
     0.560
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
  
     0.553
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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