Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
algDGDP-mannose 6-dehydrogenase (algD). (427 aa)    
Predicted Functional Partners:
galU
UTP-glucose-1-phosphate uridylyltransferase (galU).
  
 0.996
galE-2
UDP-glucose 4-epimerase, putative (galE); Does not match IPR005888 dTDP-glucose 4,6-dehydratase entry.
 0.961
galE-1
UDP-glucose 4-epimerase (galE).
 0.960
manA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase, bifunctional enzyme (manA/manC); Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.886
TGAM_0017
Sugar-phosphate nucleotydyltransferase.
  
 
 0.856
TGAM_0642
Sugar-phosphate nucleotydyltransferase.
  
 
 0.846
TGAM_1107
Sugar-phosphate nucleotydyltransferase.
  
 
 0.846
TGAM_2148
Glycosyltransferase, family 2.
  
  
 0.824
TGAM_0004
Polysaccharide biosynthesis protein; 10 probable transmembrane helices predicted by modhmm.
  
  
 0.770
TGAM_2142
Glycosyltransferase, family 1.
 
  
 0.764
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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