Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGAM_2154Conserved hypothetical protein; Belongs to DUF354 family. (356 aa)    
Predicted Functional Partners:
TGAM_2153
Glycosyltransferase, family 2; 2 probable transmembrane helices predicted by modhmm.
 
  
 0.876
pigl
N-acetylglucosaminylphosphatidylinositol deacetylase, putative (Pigl).
 
     0.858
TGAM_2156
Carbamoylphosphate synthase large subunit region, short form.
 
     0.833
TGAM_2152
NDP-sugar dehydrogenase, containing HINT/DOD homing endonuclease intein; Intein span: 280 - 748.
 
   
 0.685
TGAM_2149
Acetyl/acyl transferase related protein.
 
    0.601
TGAM_2151
Oxidoreductase, substrate unknown; Belongs to the GFO/IDH/MOCA family.
 
     0.566
degT
Pleiotropic regulatory protein, pyridoxal-phosphate-dependent aminotransferase (degT); Belongs to the DegT/DnrJ/EryC1 family.
  
    0.505
TGAM_0015
Conserved hypothetical protein; Belongs to DUF1616 family; 5 probable transmembrane helices predicted by modhmm.
 
     0.450
algD
GDP-mannose 6-dehydrogenase (algD).
 
     0.449
TGAM_2145
Glycosyltransferase, family 1, putative.
 
     0.437
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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