node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFS29743.1 | SFS48662.1 | SAMN04488006_0268 | SAMN04488006_1604 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.919 |
SFS29743.1 | SFS48668.1 | SAMN04488006_0268 | SAMN04488006_1605 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.867 |
SFS29743.1 | SFS48675.1 | SAMN04488006_0268 | SAMN04488006_1606 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.881 |
SFS29743.1 | SFS53163.1 | SAMN04488006_0268 | SAMN04488006_1882 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.416 |
SFS29743.1 | SFS53176.1 | SAMN04488006_0268 | SAMN04488006_1883 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Acetolactate synthase, small subunit. | 0.907 |
SFS29743.1 | SFS53187.1 | SAMN04488006_0268 | SAMN04488006_1884 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Acetolactate synthase, large subunit. | 0.949 |
SFS29743.1 | SFS53222.1 | SAMN04488006_0268 | SAMN04488006_1887 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.919 |
SFS29743.1 | leuB | SAMN04488006_0268 | SAMN04488006_1603 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.903 |
SFS29743.1 | leuB-2 | SAMN04488006_0268 | SAMN04488006_1889 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.903 |
SFS48662.1 | SFS29743.1 | SAMN04488006_1604 | SAMN04488006_0268 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.919 |
SFS48662.1 | SFS48668.1 | SAMN04488006_1604 | SAMN04488006_1605 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.986 |
SFS48662.1 | SFS48675.1 | SAMN04488006_1604 | SAMN04488006_1606 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.992 |
SFS48662.1 | SFS53163.1 | SAMN04488006_1604 | SAMN04488006_1882 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.756 |
SFS48662.1 | SFS53176.1 | SAMN04488006_1604 | SAMN04488006_1883 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, small subunit. | 0.932 |
SFS48662.1 | SFS53187.1 | SAMN04488006_1604 | SAMN04488006_1884 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, large subunit. | 0.899 |
SFS48662.1 | SFS53222.1 | SAMN04488006_1604 | SAMN04488006_1887 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.915 |
SFS48662.1 | ilvD | SAMN04488006_1604 | SAMN04488006_1885 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.891 |
SFS48662.1 | leuB | SAMN04488006_1604 | SAMN04488006_1603 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.970 |
SFS48662.1 | leuB-2 | SAMN04488006_1604 | SAMN04488006_1889 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.798 |
SFS48668.1 | SFS29743.1 | SAMN04488006_1605 | SAMN04488006_0268 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.867 |