STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
thiS_1Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. (68 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.995
thiD
Phosphomethylpyrimidine kinase; Identified by similarity to SP:P76422; match to protein family HMM PF08543.
  
 
 0.893
FSU_0573
Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356.
  
 0.854
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.850
FSU_0171
Putative adenylyltransferase ThiF; Identified by match to protein family HMM PF00899; match to protein family HMM TIGR02354.
  
  0.847
FSU_0144
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.817
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.817
thiH
Thiazole biosynthesis protein ThiH; Identified by similarity to SP:P30140; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR02351.
  
 
  0.808
FSU_0568
Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.
  
 0.714
FSU_2467
Menaquinone biosynthesis protein, SCO4550 family; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR03699.
  
 
  0.644
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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