STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemBPorphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family. (321 aa)    
Predicted Functional Partners:
hemDX
Porphyrin biosynthesis protein HemDX; Also 4.2.1.75; identified by similarity to GB:AAK00606.1; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469.
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.982
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.
 
 
 0.977
FSU_0300
Siroheme synthase; Identified by match to protein family HMM PF01903; match to protein family HMM TIGR01470.
 
  
 0.964
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.832
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
    
 0.581
fabD
[acyl-carrier-protein] S-malonyltransferase; Identified by similarity to SP:P25715; match to protein family HMM PF00698; match to protein family HMM TIGR00128.
 
    
 0.580
FSU_0298
Mechanosensitive ion channel family protein; Identified by match to protein family HMM PF00924.
       0.580
FSU_0302
Putative deoxycytidylate deaminase; Identified by match to protein family HMM PF00383.
       0.564
FSU_1271
Conserved hypothetical protein; Identified by similarity to GB:AAN24235.1.
  
 
 0.554
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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