STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_0300Siroheme synthase; Identified by match to protein family HMM PF01903; match to protein family HMM TIGR01470. (298 aa)    
Predicted Functional Partners:
hemDX
Porphyrin biosynthesis protein HemDX; Also 4.2.1.75; identified by similarity to GB:AAK00606.1; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469.
 
 0.999
hemB
Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.
 
  
 0.964
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.
 
  
 0.918
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 
 0.869
FSU_2156
Phosphoadenosine phosphosulfate reductase domain protein; Identified by match to protein family HMM PF01507.
  
  
 0.867
cysD
Sulfate adenylyltransferase, subunit 2; Identified by similarity to SP:P21156; match to protein family HMM PF01507; match to protein family HMM TIGR02039.
  
  
 0.865
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 
 0.808
FSU_3023
Conserved hypothetical protein; Identified by similarity to PIR:H70859.
    
 0.737
FSU_0305
nirD domain protein; Identified by similarity to PIR:G83581.
 
 
 0.725
FSU_2192
Phosphate transporter family protein.
  
  
 0.661
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
Server load: low (22%) [HD]