Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rlmHConserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (153 aa)    
Predicted Functional Partners:
FSU_0879
Identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090.
  
  
 0.874
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.786
FSU_0415
Identified by match to protein family HMM PF00149.
       0.773
FSU_0412
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254.
       0.648
FSU_0416
Peptidyl-prolyl cis-trans isomerase, FKBP-type; Identified by match to protein family HMM PF00254.
       0.555
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.555
nadD
Putative nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.496
FSU_0621
Conserved domain protein; Identified by similarity to SP:Q8TTI1; match to protein family HMM PF04101.
  
     0.448
prmA
Ribosomal protein L11 methyltransferase; Identified by similarity to SP:P28637; match to protein family HMM PF05175; match to protein family HMM PF06325; match to protein family HMM PF08241.
 
  
 0.416
FSU_3114
Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095.
 
   
 0.402
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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