STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_0504PDZ/thioredoxin domain protein; Identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534. (255 aa)    
Predicted Functional Partners:
FSU_0252
Identified by match to protein family HMM PF00023.
   
 0.929
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.919
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.896
FSU_2334
Putative chaperone protein DnaK; Identified by match to protein family HMM PF00012.
  
 0.896
trxB
Thioredoxin-disulfide reductase; Identified by similarity to SP:P50971; match to protein family HMM PF01134; match to protein family HMM PF07992.
  
 0.885
FSU_0569
Mov34/MPN/PAD-1 family protein; Identified by similarity to GB:CAE10107.1; match to protein family HMM PF01398.
    
 0.863
FSU_0570
Identified by match to protein family HMM PF01398.
    
 0.863
sodB
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.850
FSU_0522
Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
   
 0.847
FSU_2935
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.845
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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