STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBcobB protein; Identified by similarity to GB:AAC78722.1; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. (229 aa)    
Predicted Functional Partners:
FSU_0004
NAD+ synthetase, glutamine-dependent; Identified by match to protein family HMM PF02540; match to protein family HMM TIGR00552; Belongs to the NAD synthetase family.
    
 0.931
gdhA
NADP-specific glutamate dehydrogenase; Identified by similarity to SP:P00370; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.931
nadE
NAD+ synthetase, glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.931
nadD
Putative nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.924
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.915
FSU_0925
Hydrolase, NUDIX family; Identified by similarity to GP:28272372; match to protein family HMM PF00293; match to protein family HMM PF09297.
    
  0.906
FSU_0507
Peptidase, M20/M25/M40 family; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687.
   
   0.811
FSU_1321
ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
 0.811
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.767
FSU_1675
TfoX N-terminal domain protein; Identified by match to protein family HMM PF04993.
    
   0.733
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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