Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FSU_0558O-acetylhomoserine sulfhydrylase; Identified by similarity to PIR:T44655; match to protein family HMM PF01053; match to protein family HMM TIGR01326. (451 aa)    
Predicted Functional Partners:
metXW
Homoserine O-acetyltransferase/methionine biosynthesis protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.929
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.845
FSU_0559
Conserved hypothetical protein; Identified by similarity to GB:CAE27786.1.
    
  0.802
FSU_0560
Conserved hypothetical protein; Identified by similarity to GB:CAE27785.1; match to protein family HMM PF07883.
   
   0.781
FSU_0576
Putative serine acetyltransferase; Identified by similarity to SP:Q59967; match to protein family HMM PF00132.
    
 0.577
cysE
Serine acetyltransferase; Identified by similarity to SP:P05796; match to protein family HMM PF00132; match to protein family HMM PF06426.
    
 0.577
FSU_1487
Putative D-methionine-binding lipoprotein MetQ; Identified by similarity to GB:AAO58686.1; match to protein family HMM PF03180.
  
    0.514
FSU_0561
Putative membrane protein; Identified by similarity to OMNI:NTL01CA0536.
       0.498
FSU_1537
Putative cystathionine beta/gamma-lyase; Identified by similarity to SP:Q9RAS9; match to protein family HMM PF01053.
 
 
0.480
FSU_2156
Phosphoadenosine phosphosulfate reductase domain protein; Identified by match to protein family HMM PF01507.
  
 
 0.477
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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