STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FSU_0619Conserved hypothetical protein; Identified by similarity to GB:AAS08109.1. (269 aa)    
Predicted Functional Partners:
nuoBC
NADH-quinone oxidoreductase, B/C subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.841
FSU_0954
Sulfate permease; Identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF01740; match to protein family HMM TIGR00815.
    
   0.749
FSU_0620
Hypothetical protein; Identified by glimmer; putative.
       0.693
FSU_0621
Conserved domain protein; Identified by similarity to SP:Q8TTI1; match to protein family HMM PF04101.
       0.693
nuoM_1
NADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P31978; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
    
 0.649
nuoM_2
NADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
    
 0.649
guaA
GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.
    
  0.593
FSU_0622
Putative membrane protein; Identified by match to protein family HMM PF08305.
       0.557
pyrF
Orotidine 5`-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM PF00215; match to protein family HMM TIGR02127.
    
  0.419
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.418
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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