STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fumBFumarate hydratase, class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (545 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.979
fdrB
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by similarity to SP:P08066; similarity to SP:P17596; match to protein family HMM PF00037; match to protein family HMM PF00111.
  
 
 0.964
FSU_3070
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by similarity to SP:P00364; similarity to SP:P08066; match to protein family HMM PF00037; match to protein family HMM PF00111.
  
 
 0.964
FSU_0547
Putative adenylylsulfate reductase, alpha subunit; Identified by similarity to GB:CAA93322.1; match to protein family HMM PF00890; match to protein family HMM PF03486; match to protein family HMM PF07992.
  
 
 0.947
fdrA
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; Identified by similarity to SP:P08065; similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811.
  
 
 0.947
maeB
NADP-dependent malic enzyme; Identified by similarity to SP:P76558; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
  
 
 0.877
FSU_2171
Conserved hypothetical protein; Identified by similarity to GB:AAO35065.1.
   
 
 0.758
FSU_3234
Identified by match to protein family HMM PF03972.
  
 
  0.726
nifJ
Pyruvate synthase; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
  
  
 0.718
FSU_0808
Hypothetical protein; Identified by glimmer; putative.
       0.709
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.