STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (223 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5`-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM PF00215; match to protein family HMM TIGR02127.
 
 
 0.998
FSU_0506
Dihydroorotate oxidase; Identified by similarity to SP:P45477; match to protein family HMM PF01180.
  
 0.989
FSU_0664
Putative dihydroorotase, multifunctional complex type; Identified by similarity to SP:P48795.
  
  
 0.895
pyrB
Aspartate carbamoyltransferase; Identified by similarity to SP:Q59711; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.895
carA
Carbamoyl-phosphate synthetase, small subunit; Identified by similarity to SP:P25993; match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.
  
  
 0.884
pyrR
pyrR bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
  
 0.879
FSU_2151
Xanthine-uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173.
  
  
 0.872
carB_1
Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P38100; match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM PF08443; match to protein family HMM TIGR01369; Belongs to the CarB family.
  
 
 0.857
carB_2
Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P00968; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family.
  
 
 0.857
prs
Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.
  
 
 0.847
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.