STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
FSU_0937Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. (846 aa)    
Predicted Functional Partners:
FSU_0971
Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518.
 
 
 0.987
FSU_1312
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.945
FSU_1479
Conserved hypothetical protein; Identified by similarity to GB:AAO79205.1; match to protein family HMM PF08885.
  
     0.746
secDF
Protein-export membrane protein SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.699
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 
0.657
metS
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.622
FSU_0936
Hypothetical protein; Identified by glimmer; putative.
       0.554
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
  
  
 0.535
hisS
histidine--tRNA ligase; Identified by similarity to SP:P56194; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442.
 
  
 0.513
FSU_0934
Putative transporter; Identified by similarity to GB:AAN68395.1.
 
     0.464
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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