| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FSU_0937 | FSU_0971 | FSU_0937 | FSU_0971 | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | 0.987 |
| FSU_0937 | FSU_1479 | FSU_0937 | FSU_1479 | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | Conserved hypothetical protein; Identified by similarity to GB:AAO79205.1; match to protein family HMM PF08885. | 0.746 |
| FSU_0937 | gyrA | FSU_0937 | FSU_0778 | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.657 |
| FSU_0937 | hisS | FSU_0937 | FSU_3184 | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | histidine--tRNA ligase; Identified by similarity to SP:P56194; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | 0.513 |
| FSU_0937 | secDF | FSU_0937 | FSU_1302 | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | Protein-export membrane protein SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.699 |
| FSU_0971 | FSU_0937 | FSU_0971 | FSU_0937 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | 0.987 |
| FSU_0971 | FSU_1321 | FSU_0971 | FSU_1321 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614. | 0.869 |
| FSU_0971 | FSU_1479 | FSU_0971 | FSU_1479 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Conserved hypothetical protein; Identified by similarity to GB:AAO79205.1; match to protein family HMM PF08885. | 0.648 |
| FSU_0971 | dnaN | FSU_0971 | FSU_1802 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.611 |
| FSU_0971 | gltB | FSU_0971 | FSU_2320 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Glutamate synthase, large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.483 |
| FSU_0971 | gyrA | FSU_0971 | FSU_0778 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.994 |
| FSU_0971 | hepA | FSU_0971 | FSU_0598 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | RNA polymerase-associated protein HepA; Identified by similarity to SP:P23852; match to protein family HMM PF00176; match to protein family HMM PF00271. | 0.806 |
| FSU_0971 | hisS | FSU_0971 | FSU_3184 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | histidine--tRNA ligase; Identified by similarity to SP:P56194; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | 0.545 |
| FSU_0971 | secDF | FSU_0971 | FSU_1302 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Protein-export membrane protein SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.507 |
| FSU_0971 | truB | FSU_0971 | FSU_2845 | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.570 |
| FSU_1321 | FSU_0971 | FSU_1321 | FSU_0971 | ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614. | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | 0.869 |
| FSU_1321 | dnaN | FSU_1321 | FSU_1802 | ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.924 |
| FSU_1321 | hepA | FSU_1321 | FSU_0598 | ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614. | RNA polymerase-associated protein HepA; Identified by similarity to SP:P23852; match to protein family HMM PF00176; match to protein family HMM PF00271. | 0.959 |
| FSU_1479 | FSU_0937 | FSU_1479 | FSU_0937 | Conserved hypothetical protein; Identified by similarity to GB:AAO79205.1; match to protein family HMM PF08885. | Putative DNA topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | 0.746 |
| FSU_1479 | FSU_0971 | FSU_1479 | FSU_0971 | Conserved hypothetical protein; Identified by similarity to GB:AAO79205.1; match to protein family HMM PF08885. | Putative DNA topoisomerase IV, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | 0.648 |
