STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_0977HAD-superfamily hydrolase, subfamily IIA; Identified by match to protein family HMM PF00702. (264 aa)    
Predicted Functional Partners:
FSU_0975
Putative metal ABC transporter, ATP-binding protein; Identified by similarity to SP:Q9XDA6; match to protein family HMM PF00005.
       0.773
FSU_0976
Putative metal ABC transporter, periplasmic metal-binding adhesion liprotein; Identified by match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
       0.773
FSU_0974
Conserved hypothetical protein; Identified by similarity to GB:AAO90578.1.
 
     0.730
guaA
GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.
    
  0.618
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.586
FSU_0051
acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.
  
 
  0.571
FSU_0978
Conserved hypothetical protein TIGR00046; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.564
FSU_0109
Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family.
 
 
 0.506
FSU_2203
Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248.
  
 
 0.504
rdgB
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.489
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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