STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (323 aa)    
Predicted Functional Partners:
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.994
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.990
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 
 0.829
bioW
6-carboxyhexanoate--CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
  
  
 0.790
FSU_0716
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022; match to protein family HMM PF08241; match to protein family HMM PF08242.
  
 
 0.639
argF
Ornithine carbamoyltransferase; Identified by similarity to SP:P18186; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00658.
     
 0.552
FSU_2421
biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121.
  
 
 0.509
FSU_3101
Lysine 2,3-aminomutase YodO family protein; Identified by similarity to SP:P39280; match to protein family HMM PF04055; match to protein family HMM TIGR00238.
    
 0.470
coaX
Putative transcriptional activator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
     
  0.408
FSU_0969
Identified by similarity to GB:AAP09143.1; match to protein family HMM PF01177; match to protein family HMM TIGR00035; Belongs to the aspartate/glutamate racemases family.
     
  0.408
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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