Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pflBFormate C-acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255. (751 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
 0.979
nifJ
Pyruvate synthase; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
    
 0.911
nrdG
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
 
 
 0.825
pta
Phosphate acetyltransferase; Identified by similarity to SP:P45107; match to protein family HMM PF01515; match to protein family HMM TIGR00651.
   
 
 0.730
FSU_1704
Putative indolepyruvate oxidoreductase, IorB subunit; Identified by similarity to SP:O07836; match to protein family HMM PF01558.
     
 0.720
maeB
NADP-dependent malic enzyme; Identified by similarity to SP:P76558; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
  
 
 0.718
fumB
Fumarate hydratase, class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.663
FSU_2156
Phosphoadenosine phosphosulfate reductase domain protein; Identified by match to protein family HMM PF01507.
  
 
 0.612
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.610
ald
Aldehyde dehydrogenase; Identified by similarity to SP:P46329; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 
 0.607
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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