Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysK_2Cysteine synthase A; Identified by similarity to GB:AAG01002.1; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)    
Predicted Functional Partners:
cysS
cysteine--tRNA ligase; Identified by similarity to SP:Q06752; match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.894
cysE
Serine acetyltransferase; Identified by similarity to SP:P05796; match to protein family HMM PF00132; match to protein family HMM PF06426.
 
 0.846
FSU_0576
Putative serine acetyltransferase; Identified by similarity to SP:Q59967; match to protein family HMM PF00132.
 
 0.839
FSU_1526
O-acetylhomoserine sulfhydrylase; Identified by similarity to PIR:T44655; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326.
  
 
 0.738
FSU_1537
Putative cystathionine beta/gamma-lyase; Identified by similarity to SP:Q9RAS9; match to protein family HMM PF01053.
  
 0.688
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.639
trpCF
Indole-3-glycerol phosphate synthase/N-(5'-phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:O25867; match to protein family HMM PF00218; match to protein family HMM PF00697; Belongs to the TrpF family.
    
 0.624
metXW
Homoserine O-acetyltransferase/methionine biosynthesis protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
  
 
 0.609
trmU_2
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.525
FSU_2156
Phosphoadenosine phosphosulfate reductase domain protein; Identified by match to protein family HMM PF01507.
  
 
 0.477
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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