| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FSU_0130 | guaA | FSU_0130 | FSU_0249 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | 0.884 |
| FSU_0130 | guaB | FSU_0130 | FSU_3016 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.965 |
| FSU_0130 | hpt | FSU_0130 | FSU_1170 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
| FSU_0130 | purA | FSU_0130 | FSU_2115 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.982 |
| FSU_0130 | purB | FSU_0130 | FSU_0110 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.990 |
| FSU_0130 | purL | FSU_0130 | FSU_0356 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
| FSU_0130 | surE | FSU_0130 | FSU_0779 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
| argG | nadB | FSU_1067 | FSU_0012 | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.911 |
| argG | purA | FSU_1067 | FSU_2115 | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.927 |
| argG | purL | FSU_1067 | FSU_0356 | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.441 |
| argG | pyrB | FSU_1067 | FSU_0665 | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; Identified by similarity to SP:Q59711; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.904 |
| guaA | FSU_0130 | FSU_0249 | FSU_0130 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | 0.884 |
| guaA | guaB | FSU_0249 | FSU_3016 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | hpt | FSU_0249 | FSU_1170 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.950 |
| guaA | purA | FSU_0249 | FSU_2115 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.933 |
| guaA | purB | FSU_0249 | FSU_0110 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.887 |
| guaA | purL | FSU_0249 | FSU_0356 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.995 |
| guaA | pyrB | FSU_0249 | FSU_0665 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Aspartate carbamoyltransferase; Identified by similarity to SP:Q59711; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.517 |
| guaA | surE | FSU_0249 | FSU_0779 | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.948 |
| guaB | FSU_0130 | FSU_3016 | FSU_0130 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | 0.965 |
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